Changshang
Chang
2. Education:
- National
Taiwan University, Agriculture Chemistry, BS, 1978
- Taiwan
Army Chemical School (ROTC), Taiwan, Chemistry, Lieutenant, 1980
- University
of Chicago, Chicago, Illinois, Biochemistry and Molecular Biology, Ph.D.,
1985
- University
of Chicago, Chicago, Illinois, Molecular Endocrinology Postdoc, 1988
3. Professional and Academic
Experience:
- 1988-90
Assistant Professor and Director, Urology Research Labs, Dept. of
Surgery/Urology and Ben May Institute, University of Chicago, Chicago, IL
- 1990-00
Assistant Professor (90-93), Associate Professor (93-96), Professor
(96-97). Visiting Professor (97-00), Director, Tissue & Blood Bank
(90-97). Departments of Human Oncology and Medicine and UW Comprehensive
Cancer Center, University of Wisconsin, Madison, WI
- 1996-98
Visiting Professor, Department of Urology, Osaka University, Osaka, Japan
- 1998-
Visiting Professor, Oncology Institute, Xiamen University, Xiamen, China
- 1998-
Visiting Professor & Director of Andrology Lab, Dept. of Urology,
Beijing Medical Univ., China
- 1999-
Director and Adjunct Professor, Reproductive Medicine Institute, Chang
Gung University, Taiwan
- 1999-
Director and Adjunct Professor, Steroid Hormone Research Center, National
Taiwan Univ., Taiwan
- 1997-
Director, George Whipple Laboratory for Cancer Research, University of
Rochester, Rochester, NY
- 1997-
Director, Urology Research Center, University of Rochester, Rochester, NY
- 1997-
Director, Molecular Oncology Graduate Program. University of Rochester,
Rochester, NY
- 1997-
George Whipple Distinguished Professor, Departments of Pathology, Urology,
Radiation Oncology and Biochemistry, and The Cancer Center, University of
Rochester, Rochester, NY
4. Honors and Awards:
- 1988
The Ayerst Award for Outstanding Young Endocrinologist from the Endocrine
Society
- 1989
Andrew Melon Award for Outstanding Young Faculty in USA from Andrew Melon
Foundation
- 1990
Outstanding Young Investigator Award from Cancer Research Foundation
- 1991
The Milheim Award for Excellence in Cancer Research from Milheim
Foundation
- 1991-94
American Cancer Society Junior Professorship in Cancer Research
- 1995-97
Blowity-Ridgeway Award in Andrology from Blowity-Ridgeway Foundation
- 1993-99
CapCure Award (6 times) for Excellence in Prostate Cancer Research
- 1997
Award with Honorary Fellow from The Japan Society of Andrology (The 2nd
Non-Japanese ever awarded such honor)
- 1998
George Hoyt Whipple Lecture, University of Rochester, Rochester, NY
- 1998
Jiepimg Wu Award, for Outstanding Achievement in Urology (The highest
honor for Chinese-Medical Researcher). Beijing, China.
- 1999
President Award for Outstanding Urology Research, The highest honor from
The Urology Association of Taiwan for the Contribution in Androgen
Receptor and Prostate Cancer.
- 1999
Davey Memorial Award for Outstanding Cancer research, University of
Rochester.
- 1999
Scholar of the Year, The highest honor from The Taiwanese Osteoporosis
Association for Outstanding Contribution in Sex hormones and Osteoporosis.
- The Taiwanese Osteoporosis Society President誷 Award
5. Grant and Publication Review:
- 1995-
Associate Editor, Frontiers in Bioscience.
- 1999-
Member of Editorial Board, Endocrine.
- 1999-
Member of Editorial Board, The Prostate Journal
- 1994-01
NIH Study Section: Ad Hoc & Regular Member at Biochemical
Endocrinology
- 1992-96
VA Merit Grant Oncology Study Section
- 1993-95
NIH Prostate SPORE P50 Center Grant; and NIH PO1 Core Grant
- 1993-
ARMY Breast Cancer Grant Pathology Study Section
- 1992-98
Medical Research Council of Canada and Dutch Cancer Society Grant;
- 1998-
NIH Research Centers in Minority Institutes Core Grant 1996-99 Taiwan CRC
Biomedical Sciences Project and Taiwan National Science Council Grant
- 1990-
Reviewer in PNAS/JBC/Mol. Endo/Cancer Research and 16 other peer-reviewed
journals Invited Speaker: 47 International Symposia and 188
Universities/Institutes (1988-present)
6. Research Projects Ongoing or
Completed During the Last 3 Years:
·
Title I: "TR2
and TR3 Orphan Receptors in Prostate Cancer" (15% effort) -Agency:
NIH/NIDDK; RO1-DK47258, Years 5-8 (09/01/99-08/31/03). P.I.: Chawnshang Chang,
Ph.D. The goals of this project are to study the up- and down-stream regulation
of TR2/TR3 in prostate.
·
Title II: "TR4
Orphan Receptor in Testis" (15% effort) -Agency: NIH/NIDDK; RO1-DK56984,
Years 1-4 (01/01/01-12/31/04). P.I.: Chawnshang Chang, Ph.D. The goals of this
project are to study the associated proteins that may modulate TR4 function.
·
Title III:
"PTEN Tumor Suppressor in Breast Cancer" (10% effort) Agency:
ARMY/Breast Program; Idea Award, Years 1-3 (06/01/01?5/31/04). P.I.: Chawnshang
Chang, Ph.D. The goals of this project are to study the role of PTEN in breast
cancer.
·
Title IV:
"Suppression of AR Transactivation by AKT Kinase" (10% effort)
Agency: ARMY/Prostate Program; Idea Award, Years 1-3 (01/01/02?2/31/04). P.I.:
C. Chang, Ph.D. The goals of this project are to study the mechanism of Akt
signal pathway.
·
Title V
"Induction of AR Transactivation by DHT vs E2" (15% effort) -Agency:
NIH/NIDDK; RO1-DK60905, Years 1-4 (09/30/01-08/31/05). P.I.: Chawnshang Chang,
Ph.D. The goal of this project is to dissect the differences between E2 and DHT
for AR transactivation.