Analysis of N-Terminal Nucleotide
Sequence
of NDV Fusion Protein
WANG Wen-Bing,WU Xiang-Fu
( Shanghai Institute of Biochemistry,the Chinese Academy of
Sciences,Shanghai 200031,China )
JI Ping,HE Jia-Lu
( Institute of silkworm,Chinese Academy of Agricultural Sciences,Key
Laboratory of Silkworm Biotechnology,Ministry of Agriculture Zhenjiang
212018,China )
Abstract Fusion protein of Newcastle
disease virus is a glycoprotein with antigenicity. The cDNA of fusion gene of
NDV strain F48E8 was cloned by RT-PCR,and the sequence of F48E8 was compared
with other two virulent strains,Australia-victoria and Italien. Results show
that the sequences of N-terminus are very similar,and cysteine residues and the
potential glycosylation sites are relatively conserved. However,there are a few
differences in the region of signal peptides.
Key Words NDV；fusion protein；sequence；analysis
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