Reconstruction of ABC
Transporter Pathways of Archaea and Comparison of Their Genomes
XIE Tao, SHENG Quan-Hu, DING Da-Fu
( Shanghai Institute of Biochemistry, the Chinese Academy of Sciences,
Shanghai 200031, China )
Abstract Reconstruction
and comparison of metabolic pathway and regulatory network is an advanced task
in genome function prediction. In this study, many bioinformatic tools were
employed to reconstruct all ABC transporter pathways and predict their
functional features of an archaeon, Pyrococcus abyssi, on genome
scale. The comparison between ABC transporter pathways of P.abyssi and
those of another archaeon, M.jannaschii, revealed that there was no
peptide uptake ABC transporter system in M.jannaschii. This may result
from their different metabolic types.
Key words genome functional prediction； metabolic pathway； ABC transporter system； P.abyssi
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