DNA Microarray Chips
Made on Surface of Ceramic Slides
MA Wen-Li1*, ZHENG Wen-Ling2, CUI Dong2,
SONG Yan-Bin1, WU Qing-Hua1
(1Institute of Molecular Biology, The First Military Medical
University, Guangzhou 510515, China; 2Liu Hua Qiao
Hospital, Guangzhou 51010, China )
Abstract As a novel
technology, DNA microarray chips are being used in gene detections. To make DNA
chips capable of multiple probing, ceramic slides, instead of silicon wafer or
glass slides, were used as the substrate upon which DNA microarray are
deposited. Our study indicates that the ceramic DNA microarray chips can be
applied to multiple hybridization and detection procedures, showing high
specificity. The advantages in using ceramic substrates are discussed.
Key words DNA chips； ceramic substrate； gene diagnosis
Received:
October 29, 1999 Accepted: January 5, 2000
This work was supported by a grant from the National Natural
Science foundation of China, No. 39880032
* Corresponding author: Tel, 86-20-85148210; Fax,
86-20-85147755; e-mail, [email protected]