Structure of a New
Glucan from Cynanchum panilatum(Bunge)
Kitagawa
Wang Shun-Chun, He Wei, Fang Ji-Nian*
( Shanghai Institute of Materia Medica, the Chinese Academy of Sciences,
Shanghai 200031, China )
Abstract A polysaccharide
was purified from a traditional Chinese drug, “Xu-Chang-Qing” (Cynanchum
panilatum (Bunge) Kitagawa), and its molecular weight was estimated to be
1.5×104 by HPLC method. Its specific rotation [α]D was ＋151.4°(0.96, H2O).
Sugar composition analysis indicated this polysaccharide was composed only of
glucose. Methylation analysis, partially hydrolysis, acetolysis, IR and NMR
data showed that its main chain was composed of α-D 1,4 linked glucosyl
residues and its side chains were composed of α-D 1,4 and α-D 1,6 linked
glucosyl residues. There was one branch located at O-6 of the glucosyl residue
in every repeating unit containing five-glucosyl residues.
Key words Cynanchum panilatum
(Bunge) Kitagawa； glucan； chemical structure
*Corresponding author： Tel, 86-21-64311833； Fax, 86-21-64370269； e-mail, [email protected]